Frontispiece: Catalytic Enantioselective [3+2] Cycloaddition of N‐Metalated Azomethine Ylides
نویسندگان
چکیده
Pyrrolidines are intriguing scaffolds that can be found in a variety of natural products. They have numerous biological and organocatalytic uses. The asymmetric [3+2] cycloadditions employing metal catalysis with suitable chiral ligands is robust method for the synthesis enantioenriched pyrrolidines up to four centres. Recent advances summarized Review by Guiry Kumar (DOI. 10.1002/chem.202300296).
منابع مشابه
Organocatalytic enantioselective (3+2) cycloaddition using stable azomethine ylides.
We have developed a highly efficient procedure for carrying out the catalytic enantioselective (3+2) cycloaddition between enals and stable azomethine ylides such as isoquinolinium and phthalizinium methylides. Under the optimized reaction conditions highly substituted chiral pyrroloisoquinolines and pyrrolophthalazines have been obtained in high yields and excellent diastereo- and enantioselec...
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ژورنال
عنوان ژورنال: Chemistry: A European Journal
سال: 2023
ISSN: ['0947-6539', '1521-3765']
DOI: https://doi.org/10.1002/chem.202382861